Thursday, February 11, 2010

Answering to questions

By Mellitus-immunology
When under stress, will epinephrine & norepinephrine decrease the amount of lymphocytes released from the lymph nodes and from the thymus?

The thymus gland begins to shrink as a result of this . the body's immune system is not as effective in fighting off infection. If stress is overwhelming , the result are sometimes fatal.
The number of lymphocytes will decrease that is why immune system is weaker when we are stress.

The lymph nodes in response to stress and other stimuli (Shimizu et al., 1994; Madden et al., 1995a). NE signals leukocytes via cellular ß-adrenergic receptors, which activate the cAMP/PKA (protein kinase A) signaling cascade to regulate a variety of immune processes including leukocyte activation, cytokine production, and cell trafficking (Kammer, 1988; Ottaway and Husband, 1994; Madden et al., 1995a; Cole et al)
In summary it will decrease the amount of lymphocytes

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